Harnessing the power of mass spectrometry-based proteomics.

Our understanding of life today brings biology, chemistry, physics and computer science together in ways which we could never have imagined. These advances mean we can now study life and disease in such a detailed and rapid way that was not possible until only very recently.

This is the first in a series of blogs, highlighting the power of Platinum Discovery. We hope to reach a wide variety of readers, so for those not so familiar with the technicalities in this blog, here at Platinum Discovery, we are interested in proteomics  which is the large-scale study of proteomes. The proteome are the various proteins that constitute an organism or system at a particular point in time. Researching the many proteins present in a proteome can be challenging, but it is crucial to understanding life, disease onset, treatment and cure.

Mass spectrometry (MS), is a technology which dates back to the 19th century. MS is widely recognised as one of the most successful technologies for carrying out proteomic analysis. It allows one to rapidly identify and precisely quantify the thousands of proteins present in a complex biological sample.

Why is this relevant? Proteins are the functional entities of life, and the malfunction of proteins can lead to a number of conditions such as, diabetes, cancer and Alzheimer’s disease. By virtue of the very detailed understanding of the proteome, we can gain insight of a particular biological system and enable the development of highly targeted therapeutics to treat and, hopefully, cure chronic diseases. This is where we at Platinum Discovery come in. Using mass spectrometry-based proteomics, through our contract research, we help research scientists to understand the proteome, identify potential new drug targets, biomarkers and therapeutics.

Co-founded by Professor Angus Lamond, an internationally renowned proteomics expert, Platinum can trace our roots in proteomics research over 25 years.

MS-based proteomics is the only technology available that can provide an unbiased and comprehensive understanding of the proteome and modifications of the proteins. At Platinum Discovery, our next generation multidimensional proteomics allows us to give detailed understanding of proteins over time, location, abundance, isoforms or modification that give rise to complex life.

Here at Platinum Discovery, we also have the added benefit of working with our informatics experts at Platinum Desimal. Our contract research efforts are enhanced by using their leading, cloud-based software suite to help unlock insights from vast data sets.

In our next, more technical blog, I will explore in greater detail the benefits of proteomics research vs other approaches, such as genomics.

Platinum Discovery- the world’s first next-generation multidimensional proteomics contract research service.

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