Expertise

Angus is a world leading biochemist specialising in quantitative analyses of gene expression in human cells and model organisms. He is a Co-Founder and Chief Scientific Officer of Platinum Informatics. The Lamond Laboratory research how the expression of genes is controlled in human cells and it was in the Lamond Laboratory that Platinum Informatics was born. A Professor of Biochemistry at the University of Dundee since 1995, Angus has authored over 250 peer reviewed publications in major scientific journals. Angus is a distinguished speaker who is regularly invited to present his work at international conferences and seminars. He has served on numerous national and international review committees and scientific advisory boards and chaired important funding and appointment committees. After graduating with a degree in Molecular Biology from the University of Glasgow, Angus obtained his PhD in Cambridge at the MRC Laboratory of Molecular Biology and was awarded a Junior Research Fellowship at Christ’s College. Angus next moved to the USA as a postdoctoral fellow, working at M.I.T. with the Nobel Prize Winner Phillip Sharp, where he studied the mechanism of pre-mRNA splicing in mammalian cells. He then moved to Germany, where he worked for 8 years as a Group Leader at the European Molecular Biology Laboratory in Heidelberg. In Heidelberg, while Angus continued to study the mechanism of pre-mRNA splicing in human cells, he also started using mass spectrometry-based proteomics methods to analyse gene expression. Angus has 30 years’ experience in directing a multidisciplinary life sciences research laboratory, combining molecular cell biology with mass spectrometry and computational approaches, where he was an early adopter of ‘Big Data’ technologies. His research techniques have uncovered regulatory pathways that affect gene expression in the context of both health and disease, with a major current focus on studying human stem cells.